LEGEND MAX™ Human CXCL5 ELISA Kit with Pre-coated Plates 5 Pre-coated Plates

CXCL5 is a member of the CXC family of chemokines, also known as epithelial activated peptide 78 (ENA-78). The precursor of CXCL5 contains 114 amino acids, with a signal peptide of 36 amino acids which is cleaved to generate the 78 amino acids mature protein (8 kD). Human mature CXCL5 shares 57% amino acid sequence identity with mouse and rat CXCL5. Human CXCL5 also shares 41 – 77% sequence identity with CXCL1, CXCL2, CXCL3, CXCL4 CXCL6, CXCL7 and CXCL8.

CXCL5 is expressed by monocytes/macrophages, endothelial cells, vascular smooth muscle cells, epithilial cells, and eosinophils. CXCL5 is an inflammatory cytokine which binds to the cell surface receptor CXCR2 and induces chemotaxis of neutrophils to a target site. High levels of CXCL5 have been associated with prostate, gastric, and pancreatic cancer progression.

The LEGEND MAX™ Human CXCL5 (ENA-78) ELISA Kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is pre-coated with a mouse monoclonal anti human CXCL5 (ENA-78) antibody. The detection antibody is a biotinylated mouse monoclonal anti-human CXCL5 (ENA-78) antibody. This kit is specifically designed for the accurate quantitation of human CXCL5 (ENA-78) from cell culture supernatant, serum, plasma, and other biological fluids. This kit is analytically validated with ready-to-use reagents.